Diagnostic value of 5' Nucleotidase on kala - Azar patients

5'-Nucleotidase activity was measured in the sera of [67] Kala-azar patients before treatment and at different stages of treatment with pentostam as well as in [30] age matcher normal children. The changes in 5'-NT isoenzyme profile were also followed among the above cases. A change of the activity of the enzyme with the progress of the disease was observed. Our result suggest also that there are changes in the 5'-NT isoenzyme profile with the severity of the disease